Romeo and Juliet Movie Comparisons Essay Example for Free

Romeo and Juliet Movie Comparisons Essay The movie adaptations of Romeo and Juliet are immensely different, while conveying the main plot and maintaining the important parts. The settings were in two different sceneries and clothing styles. Classic version maintained the Shakespearian setting whereas the Modern version takes place in a Beach-like scenery, one could relate it to being a California scene. Although both kept the Shakespearian dialogue, their actions while speaking it were different. For example, Mercutio’s character in both kept his witty and goofy personality, yet the classic version portrayed him as immature at times. The modern version, on the other hand, portrayed him as a person who lives the party life. Also, their styles of fighting were majorly different. The classic version fought true to the time period which it takes place, using swords and daggers. Guns are the main weapons of the Modern version unlike the actual play. The movies did have some of the exact same scenes. Like the climax when Mercutio and Tybalt both die or Romeo’s banishment. But even some of the non-scripted scenes were similar. Like the play never shows the wedding between Romeo and Juliet in Friar Lawrence’s cell. The party scene where Romeo and Juliet meet is as similar as the scenery allows, it’s a masquerade. The main points of the play remained in both movies, along with the Shakespearian language. The characters basically remained the same even though they are portrayed a little different with than the other movie, since the movies were directed by two different people with different perspectives on the play.

Analysis Of Allure Magazine Usa Media Essay

Analysis Of Allure Magazine Usa Media Essay Allure, the first and only magazine devoted to beauty, is an insiders guide to a womans total image. Allure investigates and celebrates beauty and fashion with objectivity and candor, and places appearance in larger cultural context. (Allure Media Kit, 19th August 2008, p1) Well known for its pioneering approach to beauty, intelligent and truthful coverage of current issues that surround women, such as; The dangers of breast implants, eating disorders and Models addicted to heroin. Allure has been recognized for its strength and quality in journalistic writing, as well as its keen aesthetic sense seen in its photography. (Refer to appendix 3) And with it, summoned a strong following of readers that has soared to 1,150,000 (refer to appendix 1) since its beginning in 1991. (Allure Experts Reader Panel, Fas-Fax 31st December 2009) The Allure magazine is targeted towards urban women 18-49 years old with a middle income and a tertiary education. (Refer to appendix 1 2) They have a certain amount of disposable income which they enjoy spending on themselves and pride themselves in making informed choices on the products and services that they consume. In their social circle, they are influencers; informed and up to date on current affairs, trends, movies, restaurants, beauty products, fashion, music, etc. They like to be the first to know and the one that informs their friends. (Allure Experts Reader Panel, Fas-Fax 31st December 2009) Conscious about their appearance thought not obsessed by it, Allure is targeted at everyday women who are culturally universal; who dont take themselves too seriously and most of all possess a sense of humour. (Quantcast Audience Profile- Allure.com, July 2010) Allures editorial and advertising content reflects this, the products advertised and featured in Allure range from high street fashion labels; Calvin Klein Jeans, DKNY, Guess, Sisley to designer brands; Fendi, Gucci, Marc Jacobs and Coach. As for cosmetics and beauty products, the same applies; ranging from Maybelline, LOreal, Olay, Revlon, Garnier, to higher-end products; Lancà ´me, Clinique, Shiseido, Federic Fekkai, all tastefully selected with the above target market in mind. Unlike other womens magazines, Allure also contains advertising for cosmetic procedures i.e. Botox, pharmaceutical products i.e. contraceptive pills and prescription beauty products i.e. Latisse, an eyelash serum that encourages growth, showing that it does have a very specific reader. The Keatsian adage of beauty being truth and truth beauty seems also to guide the editorial philosophy of Allure; founding editor and current editor-in-chief Linda Wells. (Delving Beneath The Skin To Cover Beauty, MOSAICA, November 1998, p1) As a results of Wells innovative and bold direction, Allure has carved itself a niche amongst the traditional genre of womens magazines which concentrated solely on the latest fashion trends and beauty prescriptive; by tackling head-on some of the more serious issues that affect women. We were the first womens magazine ever to write about the dangers of breast implants, Wells explains. We did the first story on models that were addicted to heroin. Weve written about eating disorders in a way that no magazine has done. I think magazines were afraid to pull the curtains back on Oz and find out that Oz is just this little man. We pull the curtain back and say, Heres whats going on in the world.' (Delving Beneath The Skin To Cover Beauty, MOSAICA, November 1998, p1) Delving beneath the surface of beauty, fashion and womens health, Allure has been praised as the one magazine that consistently gives consumers the information that they need. With numerous awards in tow, including National Magazine Award, the Editorial Excellence Award (from Folio), and the Circulation Excellence Award (from Circulation Management), Allure is also highly regarded and recognized by the beauty industry for its truthful and informative reporting. It has won 29 awards from the American Academy of Dermatology, nine journalism awards from the Fragrance foundation, and the Excellence in Media Award from the Skin Cancer foundation. (Allure Media Kit, 19th August 2008, p1) According to Linda Wells, appearances are really important in this current day. Hence it has becomes important to women, the way in which they take care of themselves; and in the methods and process of taking care of themselves; how it makes them feel. It lifts their confidence. It gives a woman a sense of price and control. Confirming those feelings and the importance of keeping up appearances these days is something that is crucial to Allure. (QA with Linda Wells, 28th April 2009, Kaitlin Tambuscio, p2) Allure has a very strong and consistent editorial formula that has not changed over the years. (Refer to Appendix 4) Each issue has a specific editorial focus which changes according to trends and seasons, but it also has fixed features in certain issues through the year, every year i.e. Readers Choice Ballot in February, Readers Choice Awards in June, The Free Stuff Issue in August and Best of Beauty: Editors Choice Awards Breakthroughs in October. (Refer Appendix 8) In this analysis I am going to use three issues of Allure dating April 2005, August 2007 and March 2010. All three consists of six sections, listed in order; Beauty reporter, Fashion, Insiders guide, Health, Features and Regulars. There are many sub-sections within these headings but for the discussion of this paper, I am only going to discuss the few that stand out. Dedicated to beauty and acting as an insiders guide to a womans total image, Allures editorial content consists mainly of two categories, the external appearance; hair and make-up how-tos i.e. Back Stage Beauty Top 10 trends, cosmetic procedures (risks and benefits) i.e. Feature A Shot in the Dark; a growing number of women who are administering TCA peels and dubious fat-fighting injections to themselves, fashion trends i.e. Fashion Stakeout on Chloe Sevignys fashion choices, and skin care i.e. Beauty Reporter Youth Movement a review on six anti-ageing products, as well as internal well-being; physical and mental health i.e. Body News Testing Diets and Mood News Sad vs. Angry. (Allure Magazine May 2005, Condà © Nast Publications, p72, 88, 89, 139, 143, 252 168-190) Every issue consists of a balance of these two categories spread over the six sections of the magazine, contributed by a variety of writers and photographers. The sections in Allure magazine that forms the editorial format which in my opinion makes it stand out from its competitors are described as follows. Under Contributors, it highlights the contributors for that issue which are often various famous and freelance writers and photographers. This I feel gives consistent variety in terms of editorial as well as aesthetic value to the features. Beauty by numbers uses numbers and statistics to reveal interesting, unique and often humorous information about a topic in the issue which is related to beauty. (Refer to Appendix 5) Insiders Guide is a step-by-step guide by experts on three various topics including travel, beauty, entertaining and etiquette I.e. How to whiten your teeth? How to care for your shoes? How to stay cool under pressure? How to travel on your own? How to be a good houseguest? (Refer to Appendix 6) And finally, Beauty 101 a detailed pictorial guide on how-to create a look i.e. Low Ponytail, which also includes four tear-out cardboard cards for easy reference. (Refer to Appendix 7) Founded in 1991 by Editor in Chief Linda Wells, and directed by Vice President and Publisher Agnes B. Chapski since May 2008 (Allure Media Kit, 19th August 2008, p2), Allures masthead consists of almost one hundred staff (Refer to Appendix 9). It is owned by worldwide publishing company, Condà © Nast Publications which is one of the worlds most celebrated publishers. Their commitment to journalistic integrity, influential reporting and superior design combined with world-renowned editors, writers and photographers, which their magazines consistently feature; meld together to form an incredible stable of talent unmatched by any other publishing company. (A Brief History of the Condà © Nast Publications, 1993) Some examples of the prestigious lifestyle magazines that Condà © Nast Publications have under their belt are Vogue, GQ, Wired, Vanity Fair and The New Yorker, amongst many others. (Refer to Appendix 10) Hence, it is no surprise that under the same publishing umbrella, Allure has also made its name as one of the most successful and innovative publications, backed by soaring circulation figures from its initial 250,000 in 1991 to its current 1,150,000. (Allure Media Kit, 19th August 2008, p1) The Magazines Handbook suggests that the average advertising/editorial ratio of consumer magazines should be around 60:40 (McKay, Routledge 2000, p142).; containing enough advertising to generate revenue but still giving the reader value for money in terms of editorial. When the advertising content in a magazine is much more than 60%, it becomes cluttered with too many ads and according to Litman; will lose the editorial interest of the reader. (Litman, Journal of Advertising 1997, p4) This is further backed up by Halls Magazine reports 2009, which show that in the last ten years, the advertising/ editorial ratio of magazines has kept closely to the 60:40 recommendations. (Refer to Appendix 11) Hence, Allure gives its readers good value as it has managed to come under the recommended 60:40 advertising/ editorial ratio as shown in Appendix 12. HISTORY OF ALLURE MAGAZINE Allure magazine was first published in March 1991 (Refer to Appendix 13) by Condà © Nast Publications Inc., it was the first magazine entirely dedicated to beauty. Linda A. Wells is the founding editor and editor-in-chief of Allure magazine. The current editor-in-chief, Wells started Allure because she wanted to create a womens magazine that was both informative and truthful; unlike the traditional genre of womens magazines that focused on the latest fashion and beauty products, Wells wanted to give consumers the information that they needed. (Allure Media Kit, 19th August 2008, p1) Allure has been and still is currently owned by Condà © Nast Publications Inc. since its inception. At the time of its premiere issue, Kathy Leventhal was the publisher; she only stayed with Allure for two years leaving in May 1993. However, in the time that she was with the magazine, advertising pages rose from 94.9% to 462%, in the first half of 1993 from the comparable period in 1992. Circulation also jumped 41.4% for the first five issue of the year, to 669,000. (Fabrikant, The Media Business, May 1993) Since Kathy Leventhals departure, Allure has seen a few more publishers come and go. Sandy Golinkin (Carmody, The Media Business, May 1993) replaced Leventhal as publisher from May 1993 but was dismissed in 1999 because of the declining market for beauty advertising. (The New York Daily News, May 2000) Next in line was Erica Bartman who took over from Golinkin but abruptly resigned in April 2000. Shortly after in May 2000, Suzanne Grimes became publisher at Allure and she helped turn around a three year financial slide , posting a 13% increase in revenue in the first and only year she was there, she left to be the Vice President-Publisher of another Condà © Nast Publications; Glamour. (Betzold, Advertising Age, June 2001) Nancy Berger Cardone was Vice President and Publisher of Allure from 2001; she left in 2008 to become Vice President-Publisher of Gourmet. Under her leadership, Allure enjoyed seven consecutive record-breaking years, she increased advertising pages by 50% and published the largest issue in Allures history. It was also during her tenure that Allure won Ad weeks Hot List and Advertising Ages Best Performer. (Gourmet Press Centre, 2010) Finally, replacing Cardone in 2008 is Agnes B. Chapski, she is also the current Vice President-Publisher of Allure. (Allure Media Kit, 19th August 2008, p2) There are two problems that Allure encountered during its life so far; the media/digital revolution which drastically changed the way media was consumed, and the Economic Recession which significantly affected advertising revenue. In order to keep up with the digital revolution Allure launched its website Allure.com on the 17th of May 1994, the website is consistent with Allures brand as the ultimate beauty expert resource. It feature the same sections that are present in the magazine such as; The Beauty Reporter, Inside Allure, How-tos, Trends, Salon Spa directory, Makeovers and also includes interactive elements such as Free stuff, Twitter and Videos. The website also enabled you to subscribe to the magazine. (Website Traffic Spy, 2010) During the Economic Recession Allures advertising revenue plummeted 41% in January 2009 from January 2008. January 2008 had 70 pages of ads and January 2009 only had 41 according to the Media Industry Newsletter due to clients cutting their advertising budgets to cope with the recession and turning to other less established downscale publications which offered heavy discounts. In an interview by The New York Times, Jack Hanrahan said, Allure adopted a smart strategy to combat the financial recession; they negotiated with advertisers in regards to paging but not on price as they had larger bases of ad pages. As it is a private company, it does not need to report quarterly revenue. This enables them to preserve their well-established pricing-position of being equitable across advertisers and not engaging in heavy discounting and negotiations to secure a small schedule. Instead, they encouraged the advertisers annual commitment to a magazine. (Clifford, the New York Times, January 2009) As you can see, is still very much alive today. With an active website that had a monthly traffic of 487,000 readers in May 2010 and a monthly traffic which averages 208,600 readers a month, we can say that it has effectively kept up with the digital age while still maintaining its market position in print with a circulation of 1,050,000 and a readership of 6,570,000. (Allure Experts Reader Panel, Fas-Fax 31st December 2009)

Mechanism Of Action Of Warfarin Biology Essay

Mechanism Of Action Of Warfarin Biology Essay Warfarin is an anticoagulant medication that is used to prevent thrombosis (clots) and embolism in many disorders. Warfarin activity has to be monitored by frequent blood testing for the International Normalized Ratio (INR). Warfarin is a synthetic derivative of coumarin, a chemical found naturally in many plants it decreases blood coagulation by interfering with vitamin K metabolism. Mechanism of Action of Warfarin Warfarin is vitamin K antagonist that produce its anticoagulant effect by interfering with the cyclic interconversion of vitamin K and its 2,3 epoxide (vitamin K epoxide). Vitamin K is a cofactor for the posttranslational carboxylation of glutamate residues to ÃŽÂ ³-carboxyglutamates on the N-terminal regions of vitamin K-dependent proteins (Whitlon, et al., 1978; Fasco, et al., 1982) .123456 These coagulation factors (factors II, VII, IX, and X) require ÃŽÂ ³-carboxylation for their biological activity. Coumarins produce their anticoagulant effect by inhibiting the vitamin K conversion cycle, thereby causing hepatic production of partially carboxylated and decarboxylated proteins with reduced procoagulant activity.78 In addition to their anticoagulant effect, the vitamin K antagonists inhibit carboxylation of the regulatory anticoagulant proteins C and S and therefore have the potential to exert a procoagulant effect. In the presence of calcium ions, carboxylation causes a conformational change in coagulation proteins91011 that promotes binding to cofactors on phospholipid surfaces. The carboxylation reaction requires the reduced form of vitamin K (vitamin KH2), molecular oxygen, and carbon dioxide, and is linked to the oxidation of vitamin KH2 to vitamin K epoxide. Vitamin K epoxide is then recycled to vitamin KH2 through two reductase steps. The first, which is sensitive to vitamin K antagonists,123 reduces vitamin K epoxide to vitamin K1 (the natural food form of vitamin K1), while the second, which is relatively insensitive to vitamin K antagonists, reduces vitamin K1 to vitamin KH2. Treatment with vitamin K antagonists leads to the depletion of vitamin KH2, thereby limiting the ÃŽÂ ³-carboxylation of the vitamin K-dependent coagulant proteins. The effect of coumarins can be counteracted by vitamin K1 (either ingested in food or administered therapeutically) because the second reductase ste p is relatively insensitive to vitamin K antagonists (Fig 1). Patients treated with a large dose of vitamin K1 can also become warfarin resistant for up to a week because vitamin K1 accumulates in the liver and is available to the coumarin-insensitive reductase. Pharmacokinetics and Pharmacodynamics of Warfarin Warfarin is a racemic mixture of two optically active isomers, the R and S forms in roughly equal proportion. It has high bioavailability,1920 is rapidly absorbed from the GI tract, and reaches maximal blood concentrations in healthy volunteers in 90 min after oral administration.1921 Racemic warfarin has a half-life of 36 to 42 h, circulates bound to plasma proteins (mainly albumin), and accumulates in the liver where the two isomers are metabolically transformed by different pathways.22 The dose-response relationship of warfarin is influenced by genetic and environmental factors, including a recently identified common mutation in the gene coding for one of the common cytochrome P450 enzymes (2C9), the hepatic enzyme responsible for oxidative metabolism of the warfarin S-isomer.2324 This mutation likely contributes to the variability in dose response to warfarin among healthy subjects.25 In addition to known and unknown genetic factors, various disease states, drugs, and dietary fac tors can interfere with the response to warfarin. The anticoagulant response to warfarin is influenced by pharmacokinetic factors, including drug interactions that affect the absorption or metabolic clearance of warfarin, and pharmacodynamic factors that alter the hemostatic response to given concentrations of the drug. Variability in anticoagulant response also occurs as a result of inaccuracies in laboratory testing, patient noncompliance, and miscommunication between patient and physician. Other drugs may influence the pharmacokinetics of warfarin by reducing GI absorption or by disrupting its metabolic clearance. For example, the anticoagulant effect of warfarin is reduced by cholestyramine, which impairs its absorption, and is potentiated by drugs that inhibit warfarin clearance through stereoselective or nonselective pathways.252627 Stereoselective interactions affect oxidative metabolism of either the S-isoner or R-isomer of warfarin.2627 Inhibition of S-warfarin metabolism is more important clinically because this isomer is five times more potent as a vitamin K antagonist than the R-isomer.2627 Clearance of S-isomer warfarin is inhibited by phenylbutazone,2829 sulfinpyrazone,30 metronidazole,31 and trimethoprim- sulfamethoxazole,32 each of which potentiates the effect of warfarin on the prothrombin time (PT). In contrast, drugs such as cimetidine and omeprazole that inhibit clearance of the R-isomer have only moderate potentiating effects on the PT in patients treated with warfarin.272833 Amiodarone inhibits the metabolic clearance of both the S-isomer and R-isomer and potentiates the anticoagulant effect of warfarin.34 The anticoagulant effect is inhibited by barbiturates,32 rifampicin,34 and carbamazepine,32 which increase its metabolic clearance by inducing hepatic mixed oxidase activity. Although long-term alcohol use has a potential to increase the clearance of warfarin through a similar mechanism, consumption of even relatively large amounts of wine was shown in one study29 to have little influen ce on PT in subjects treated with warfarin. For a more thorough discussion of the effect of enzyme induction on warfarin therapy, the reader is referred to a critical review (Table 2 ).35 The pharmacodynamics of warfarin are subject to genetic and environmental variability. Hereditary resistance to warfarin occurs in rats36 as well as in human beings.3738 Patients with genetic warfarin resistance require doses fivefold to 20-fold higher than average to achieve an anticoagulant effect. This disorder is attributed to altered affinity of the receptor for warfarin since the plasma warfarin levels required to achieve an anticoagulant effect are increased. Two mis-sense mutations in the factor IX propeptide have been described394041 that cause bleeding without excessive prolongation of PT. When affected individuals are treated with coumarin drugs, factor IX activity decreases to about 1 to 3%, while levels of other vitamin K-dependent coagulation factors decrease to 30 to 40% of normal. These mutations are uncommon and have been estimated to occur in Subjects receiving long-term warfarin therapy are sensitive to fluctuating levels of dietary vitamin K,4243 which is provided predominantly by phylloquinone in plant material.43 The phylloquinone content of a wide range of foodstuffs has been listed by Sadowski and associates.44 Phylloquinone acts through the warfarin-insensitive reductase reaction.45 Important fluctuations in vitamin K intake occur in both apparently healthy and sick subjects.46 Increased intake of dietary vitamin K sufficient to reduce the anticoagulant response to warfarin42 occurs in patients on weight-reduction diets consuming green vegetables or receiving vitamin K-containing supplements, and in patients treated with IV supplements containing vitamin K. Reduced dietary vitamin K1 intake potentiates the effect of warfarin in sick patients treated with antibiotics and IV fluids without vitamin K supplementation and in states of fat malabsorption. Hepatic dysfunction potentiates the response to warfarin through im paired synthesis of coagulation factors. Hypermetabolic states produced by fever or hyperthyroidism increase warfarin responsiveness, probably by increasing the catabolism of vitamin K-dependent coagulation factors.4748 Drugs may influence the pharmacodynamics of warfarin by inhibiting synthesis or increasing clearance of vitamin K-dependent coagulation factors or by interfering with other pathways of hemostasis (Table 3 ). The anticoagulant effect of warfarin is augmented by the second-generation and third-generation cephalosporins, which inhibit the cyclic interconversion of vitamin K,4950 by thyroxine, which increases the metabolism of coagulation factors,48 and by clofibrate, through an unknown mechanism.51 Doses5253 of salicylates > 1.5 g/d also augment the anticoagulant effect of warfarin,54 possibly because these drugs have warfarin-like activity. Acetaminophen has also been reported to augment the anticoagulant effect of warfarin,52 although this contention has been challeng ed (see below). Although heparin potentiates the anticoagulant effect of warfarin, in therapeutic doses, it produces only slight prolongation of the PT. Drugs such as aspirin,55 nonsteroidal anti-inflammatory drugs,56 high doses of penicillins,5758 and moxolactam50 increase the risk of warfarin-associated bleeding by inhibiting platelet function. Of these, aspirin is the most important because of its widespread use and prolonged effect.59 Aspirin and nonsteroidal anti-inflammatory drugs can also produce gastric erosions that increase the risk of upper-GI bleeding.58 The risk of clinically important bleeding is heightened when high doses of aspirin are taken in combination with high-intensity warfarin therapy (INR, 3.0 to 4.5).5560 In two studies, one study61 in patients with prosthetic heart valves and the other study62 in asymptomatic individuals at high risk of coronary artery disease, low doses of aspirin (100 mg/d and 75 mg/d, respectively) were also associated with increased rates of minor bleeding when combined with moderate-intensity and low-intensity warfarin anticoagulation. The mechanisms by which erythromycin63 and some anabolic steroids64 potentiate the anticoagulant effect of warfarin are unknown. Sulfonamides and several broad-spectrum antibiotic compounds may augment the anticoagulant effect of warfarin by eliminating bacterial flora and aggravating vitamin K deficiency in patients whose diet is deficient of vitamin K.65 Wells and associates66 performed a critical analysis of articles reporting possible interaction between drugs or foods and warfarin. Studies were assigned to one category if the interaction was considered highly probable, to a second category if interaction was probable, to a third level if judged possible, and to a fourth level if doubtful. Of 751 citations retrieved, pertinent results from 172 original articles are summarized in Table 3. Strong evidence of interaction was found for 39 of the 81 different drugs and foods appraised; 17 potentiate warfarin effect, 10 inhibit, and 12 produce no effect. Many other drugs have been reported to either interact with oral anticoagulants or alter the PT response to warfarin,6768 but convincing evidence of a causal association is lacking. In a case-control study,52 low to moderate doses of acetaminophen (nine or more tablets per week) were reported to be associated with excessively prolonged INR values. The presence of a causal association bet ween acetaminophen use and potentiation of a warfarin effect is uncertain. The article52 was supported by an editorial,53 but has been challenged by personal experiences (case series) cited in two letters6970 and by the results of a prospective study71 in normal volunteers. However, until more information is presented, it would be prudent to monitor the INR more frequently when acetaminophen is used in this quantity by patients during warfarin therapy. Indeed, it would be reasonable to monitor the PT more frequently when any drug therapy is added or withdrawn from the regimen of a patient treated with an oral anticoagulant. DRUG INTERACTIONS: Your doctor or pharmacist may already be aware of any possible drug interactions and may be monitoring you for them. Do not start, stop, or change the dosage of any drug, vitamin, or herbal product without checking with your doctor or pharmacist first.Warfarin interacts with many prescription, nonprescription, vitamin, and herbal products. This includes medications that are applied to the skin or inside the vagina or rectum. The following interactions listed do not contain all possible drug interactions. The interactions with warfarin usually result in an increase or decrease in the blood-thinning (anticoagulant) effect. Your doctor or other health care professional should closely monitor you to prevent serious bleeding or clotting problems. While taking warfarin, it is very important to tell your doctor or pharmacist of any changes in medications, vitamins, or herbal products that you are taking.This drug should not be used with the following medications because v ery serious interactions may occur: imatinib, mifepristone.If you are currently using any of these medications listed above, tell your doctor or pharmacist before starting warfarin.Aspirin and aspirin-like drugs (salicylates) and nonsteroidal anti-inflammatory drugs (NSAIDs such as ibuprofen, naproxen, celecoxib) may have effects similar to warfarin. These drugs may increase the risk of bleeding problems if taken during treatment with warfarin. Carefully check all prescription/nonprescription product labels (including drugs applied to the skin such as pain-relieving creams) since the products may contain NSAIDs or salicylates. Talk to your doctor about using a different medication (such as acetaminophen) to treat pain/fever. Low-dose aspirin and related drugs (such as clopidogrel, ticlopidine) should be continued if prescribed by your doctor for specific medical reasons such as heart attack or stroke prevention. Consult your doctor or pharmacist for more details.Many herbal medicati ons have blood-thinning or blood-clotting effects, and some may directly affect warfarin. Tell your doctor before taking any herbal products, especially bromelains, coenzyme Q10, cranberry, danshen, dong quai, fenugreek, garlic, ginkgo biloba, ginseng, goldenseal, and St. Johns wort, among others.This medication may interfere with a certain laboratory test to measure theophylline levels, possibly causing false test results. Make sure laboratory personnel and all your doctors know you use this drug.This document does not contain all possible interactions. Therefore, before using this product, tell your doctor or pharmacist of all the products you use. Keep a list of all your medications with you, and share the list with your doctor and pharmacist

Crime And Drugs :: Crime Drugs Research Papers

Crime and Drug Use The link between drug use and crime is not a new one. For more than twenty years, both the National Institute on Drug Abuse and the National Institute of Justice have funded many studies to try to better understand the connection. One such study was done in Baltimore on heroin users. This study found high rates of criminality among users during periods of active drug use, and much lower rates during periods of nonuse (Ball et al. 1983, pp.119-142). A large number of people who abuse drugs come into contact with the criminal justice system when they are sent to jail or to other correctional facilities. The criminal justice system is flooded with substance abusers. The need for expanding drug abuse treatment for this group of people was recognized in the Crime Act of 1994, which for the first time provided substantial resources for federal and state jurisdictions. In this paper, I will argue that using therapeutic communities in prisons will reduce the recidivism rates among people who have been released from prison. I am going to use the general theory of crime, which is based on self-control, to help rationalize using federal tax dollars to fund these therapeutic communities in prisons. I feel that if we teach these prisoners some self-control and alternative lifestyles that we can keep them from reentering the prisons once they get out. I am also going to describe some of today’s programs that have proven to be very effective. Gottfredson and Hirschi developed the general theory of crime. It According to their theory, the criminal act and the criminal offender are separate concepts. The criminal act is perceived as opportunity; illegal activities that people engage in when they perceive them to be advantageous. Crimes are committed when they promise rewards with minimum threat of pain or punishment. Crimes that provide easy, short-term gratification are often committed. The number of offenders may remain the same, while crime rates fluctuate due to the amount of opportunity (Siegel 1998). Criminal offenders are people that are predisposed to committing crimes. This does not mean that they have no choice in the matter, it only means that their self-control level is lower than average. When a person has limited self-control, they tend to be more impulsive and shortsighted. This ties back in with crimes that are committed that provide easy, short-term gratification. These people do not necessarily have a tendency to commit crimes, they just do not look at long-term consequences and they tend to be reckless and self-centered (Longshore 1998, pp.

Career Research: Nursing :: Career Research

Deciding which career is best for me is a very difficult decision. There are so many different types and areas of study to choose from and many that I am interested in. Ever since I was little I have always wanted to become a nurse. When I was ten years old, my grandmother experienced a stroke right in front of me. No other adult was home at the time and I had to manage the experience alone. I remained calm and took care of her until emergency personnel arrived to take over her medical needs. Everything ended well with her and I felt that I managed everything with maturity. Later on, at age thirteen, I also observed the process of this same grandparent going through a battle with breast cancer. Because of these experiences, the idea of a nursing career blossomed and has stuck with me the longest. So many different aspects of a nurse appeal to me and there is a huge selection of various fields of nursing, any of which I could specialize in. Interestingly, teaching mathematics has al so always been appealing to me. The idea of having a math degree did not present itself until I started college and scored so well in entrance exams. There are a lot of benefits that come along with being a teacher and it is a job I know I would enjoy. After exploring various math related careers with a family friend (and Dean of Math Studies at Washington University), I decided that I would be good at working in a school district teaching math at various levels. I have also explored the career of being a high school counselor and feel it would be a great career for me for numerous reasons. Growing up, I have watched my mother work in the counseling field and have decided that it is a career that would never get old and would always give me new challenges. All of these career choices are in fields that are helpful to other people, which is what I know I would do best. No matter which career I choose, I know that I will be benefiting and helping people every day. Because nursing seems to be the best match for my interests, I feel that going into the field of nursing would be best for me. The opportunities are almost endless in nursing.

polar bears :: essays research papers

Polar Bear, common name for a white bear found on the sea ice of the Arctic throughout the North Polar basin. The only marine bear, it is longer than other bears and streamlined for aquatic life. It has the plantigrade feet (heel and sole touching the ground) typical of bears, with five sharp, curved claws on each foot for grasping the ice and holding its prey. Long hair between the pads protects the bear's feet from the cold and provides traction on the ice. Stiff hairs on the forelegs, and very broad front feet, help the bear swim. All polar bears are white, although their fur may yellow in the summer. The largest wild bears ever weighed—more than 800 kg (1760 lb)—have been polar bears. However, most male polar bears weigh an average of about 350 kg (about 880 lb), and most females weigh about 250 kg (550 lb). Polar bears have a strong navigational sense, an extremely good sense of smell, and they are unusually clever at solving problems in order to obtain food. They eat primarily ringed seals, and occasionally bearded seals, walruses, or white whales. They also feed on berries, sedges, mussels, and kelp. As with other true bears, polar-bear mothers and young form strong bonds. The young are very small when born: about 1 kg (about 2 lb). Their eyes remain closed for about 40 days and they must nurse every few hours. The mother holds them close to keep them warm. Except during the breeding season, male polar bears are solitary and roam over vast expanses of sea ice while hunting. During the breeding season (May to June), the males fight furiously over females.

Descriptive Names

THE PEARL OF THE ORIENT SEAS During the early ages, many Filipinos use pearls for accessories. The Philippines as we all know is really surrounded by different bodies of water because of these, many sea divers dive in seas just to get big and beautiful pearls. The Philippines is also rich in natural resources containing beautiful places because to these, they export different sizes of pearls in the different parts of the country. With all its grandeur and magnificence, the Pearl of the Orient Seas lays claim to its naturally abundant environment with beautiful beaches and enthralling panoramic sights.In the past few decades the Philippines have been frequented by tourists for countless reasons. The Philippine sunset is one of the most breathtaking views one could ever see. You would love to feel that fleeting bliss when you see the sky tinted with scarlet, the scarcely diffused light of the setting sun as twilight unfolds. VOCABULARY: GRANDUER – the quality or condition of bei ng grand magnificent ENTHRALLING – something you enjoy and give your complete attention and interestFLEETING – used to describe something which only last for a very short time REFLECTION: Philippines is a beautiful place which is abundant with natural resources especially different kind of pearls. The Philippine sunset is the most beautiful creation that God has given. With these abundance tourist love to come in the Philippines. The Philippines was named the The Pearl of the Orient Seas because of its abundance of pearls which is located in the Philippine Sea Jean Aeriel Marie A. Manansala Gr. 4 – CourtesyTHE LAND OF THE RISING SUN The Japanese called their country, Nihon, which means â€Å"the source of the sun† or â€Å"the land of the rising sun†, because it is so far east. It is a land of mountains and lakes, of great cities and skyscrapers. And it is one of the wealthiest and most technologically advanced countries of the world. The Japanese built their national and cultural heritage on a chain of volcanic islands. The transition from a closed society to one that opened to the outside world had a profound effect on Japan.Even today, when Japan is super-modern and technological, it retains a stark conservativeness and guards its unique tradition very closely. Our tour provides a wonderful opportunity to visit this amazing country where the ancient and the innovative are wonderfully interwoven; contemporary and traditional architecture embrace one another; amazing scenery and bustling cities; and polite, welcoming people everywhere. VOCABULARY: SKYCRAPERS – a very tall buildings INTERWOVEN – very closely connected or are combined with each otherBUSTLING – a place with people with very busy or lively activities REFLECTION: Japan is one of the most polite country in the world. The Japanese are so hospitable with tourist. Japan is one of the most advance country. Japan is a place where people will be ama zed because of its ancient and heritage living. Jean Aeriel Marie A. Manansala Gr. 4 – Courtesy THE LAND OF GOLDEN PAGODAS Myanmar, formerly known as Burma, is recognized by the world as the Golden Land. It is one of the earliest homes of mankind, where one can have exclusive experiences of a life-time.You have to find out why. Myanmar, officially Union Of Myanmar, also called Burma, Burmese Myanmar, or Pyidaungzu Myanmar Naingngandaw, is a country lying along the eastern coasts of the Bay of Bengal and the Andaman Sea in southeast Asia. It is a land of hills and valleys and is rimmed in the north, east and west by mountain ranges forming a giant horseshoe. Enclosed within the mountain barriers are the flat lands of Ayeyarwaddy, Chindwin and Sittaung River valleys where most of the country's agricultural land and population are concentrated.Myanmar is endowed with a rich diversity of habitat types arising largely from its unusual ecological diversity. It is home to nearly 300 known mammal species, 300 reptiles and about 100 birds species, and a haven for about 7,000 species of plant life. Since Myanmar considers such a rich pool of bio diversity as an important national asset, the Government has drawn up strict regulations to protect its biological resources. As some folktales have said, the map of the country itself resembles the figure of a dancing lady. VOCABULARY:RIMMED – has color or substance around its border BARRIERS – something that makes it difficult or impossible for something to happen or be achieved. ENDOWED – desirable ability, characteristic, or possession that ones have which they have by birth or by chance. REFLECTION: Myanmar is a place of mankind where we can experience in a life time. Myanmar is a beautiful place where we can find different kinds of animals. It is a place where one should go and experience the beauty of nature. Jean Aeriel Marie A. Manansala Gr. 4 – Courtesy THE TINY DRAGON OF ASIALying on the eastern part of the Indochinese peninsula, Vietnam is a strip of land shaped like the letter â€Å"S†. China borders it to the north, Laos and Cambodia to the west, the East Sea to the east and the Pacific Ocean to the east and south. Vietnam is considered one of the most popular destinations in the south-east of Asia. Hanoi, the capital of the country, is an ancient city, the political, economic and cultural center. The city began its rapid development in the 11th century, when the Emperor Wan Li Kong, moved his capital to the citadel of Thang-Long.Today it is one of the most interesting cities in Asia, with its wide avenues and European-style skyscrapers, numerous lakes, parks and fountains interspersed with hundreds of colonial houses and pagodas. VOCABULARY: RAPID – fast or quick CITADEL – a strong building where people could shelter for safety INTERSPERSED – the second thing happen or occur between or among the first thing REFLECTION: Vietnam is a land which is shaped like a letter â€Å"S†. Vietnam has a lot of ancient cities where tourist are fun of. With Vietnam’s development it is now one of the most exciting place in Asia because of its wide avenues and tall buildings.Jean Aeriel Marie A. Manansala Gr. 4 – Courtesy RICHEST NATION IN SOUTHEAST ASIA From the 14th to the 16th century, Brunei was the center of a powerful native sultanate occupying what are now Sabah and Sarawak and extending northward through the Philippines almost to Manila. By the 19th century, much of this empire had been whittled away by war, piracy, and the colonial expansion of European nations. During the 1970s, Brunei emerged as the richest state in Southeast Asia, profiting from its oil wealth and the steep increases in international oil prices.Much of this vast oil income has been expended by the state on modernization and social services. VOCABULARY: WHITTED – having wits or understanding, intelligence as specified C OLONIAL – controlled by powerful countries VAST – extremely large REFLECTION: Brunei is one of the most richest country in the world. Brunei is lead by a sultan. Brunei uses its own natural resource to develop their country most especially their oil wealth. This is why Brunei was named as the richest nation in Southeast Asia. Jean Aeriel Marie A. Manansala Gr. 4 – Courtesy THE LAND OF JEWELSSri Lanka – the teardrop shaped nation, said to be the jewel of the Orient has always attracted travelers to its shores because of its white beaches, beautiful historic ruins and fascinating culture. The land of spices, nature and history. Floating like an emerald jewel in the dreamy Indian Ocean, the captivating isle of Sri Lanka stands as testament to the beauty of Mother Nature’s handiwork. One of Asia's most biologically diverse countries, Sri Lanka is home to elephants, leopards, buffalo, deer, monkeys, squirrels, snakes, chameleons as well as hundreds of b ird species.The island of Sri Lanka, also known as â€Å"Ceylon† has a long heritage for gem-mining and trading that dates back some 2,000 years. Sri Lanka is a tropical island situated in the Indian Ocean, off the southeastern tip of India. Sri Lanka has earned its namesake as the â€Å"Island of Gems,† or â€Å"Gem Island† (Ratna Dweepa), with its abundance of corundum gems, chrysoberyl and alexandrite, garnet, moonstone, peridot, spinel, topaz, tourmaline, and zircon. Sri Lanka has been known by many different names. Due to the rich gem stone deposits, the Arabs named it ‘Serendip' meaning â€Å"Island of Jewels'.VOCABULARY: RUINS – a part or remains after it has been damaged or destroyed HERITAGE – qualities, traditions or features of life that have been continued over many years and have been passed on from one generation to another CORUNDUM – an extremely hard mineral REFLECTION: Sri Lanka attracts its tourist because of the bea uty of its white beaches, historic places and fascinating cultures. Sri Lanka proves the beauty of Mother Nature’s handworks. Sri Lanka is abundant with gems this is why it was called the land of jewels.